For PDF files that are intended to be distributed for viewing purposes only, you may want to reduce the size of PDF files when you export from InDesign. Here are some of the size reduction techniques you can use in the Export Adobe PDF dialog box:
Choose [Smallest File Size] from the Adobe PDF Preset menu.
In the Compression area, downsample images to 72 pixels per inch, select automatic compression, and select either low- or medium-image quality for color and grayscale images. When you work with photographic images, use Automatic (JPEG 2000) compression; when you work with images that are mostly solid color, such as charts and graphs, use ZIP compression.
In the Output area, use the Ink Manager to convert spot colors to process colors.
For more information on reducing the size of PDF files, see Acrobat Help and the Adobe website.